Vaccine Development

Vaccine Development

Vaccine Development

Read:

Watch :&νβσπ; &νβσπ;&νβσπ;The Vaccine War https://www.pbs.org/wgbh/frontline/film/vaccines/  

 

Discussion: Vaccines are responsible for many global public health successes, such as the eradication of smallpox and significant reductions in other serious infections like polio and measles.

Vaccines are tested in thousands of individuals and in combination with other vaccines prior to licensure.  Rigorous standards for both efficacy and safety need to be met before a vaccine can be licensed. Even so, vaccinations have also long been the subject of various ethical controversies.

 

Questions:

 

  • Describe and discuss clinical trials and the FDA approval process of vaccine development. Do challenge trials such as the one discussed in the reading above fulfill these criteria?   What is an emergency use authorization as opposed to an approved designation for a vaccine?
  • Discuss key ethical and legal debates related to vaccine development and use. Reflect on the reading from George Annas above. Do you see any correlation between the discussions generated by vaccine development and distribution for Ebola and COVID19?  What about vaccine hesitancy?
  • Research one religious perspective on vaccination and explain why it either supports or opposes vaccination. For those religious individuals who oppose vaccinations, how might vaccines be developed or manufactured differently to avoid the conflict between vaccination and religion?

**At least three recent peer-reviewed literature references should be cited for your discussion.