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main events of toxicity such as primary

main events of toxicity

Mass media coverage of the thalidomide tragedy brought the field of developmental toxicology to the attention of the public. For the first time, it was tragically demonstrated that a chemical agent had the potential to profoundly affect human development. Responsible scientists and members of the regulatory community recognized that developmental toxicity might not be unique to thalidomide. It was soon realized that the toxicity testing methods for pharmaceutical products in use at that time were focused primarily on the adult and were inadequate to predict the response or susceptibility of the embryo or fetus.

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