Controversies in Global Control and Eradication of Infectious Diseases
Controversies in Global Control and Eradication of Infectious Diseases. The science and discovery of new and innovative vector and disease control methods is expanding rapidly. From gene drive to bacterial superinfection of vectors (e.g. Wolbachia) to new plant-based vaccine strategies to phone-based surveillance and/or compliance methods, these new methodologies have the potential to markedly extend our disease control reach. This paper will be a comprehensive review of new and innovative control strategies that have recently been deployed or are in the planning or conceptual stages. Some examples are: 1) Social network-based gamification of vector control strategies; 2) depot methods of pharmaceutical prophylaxis; 3) sterile male vector introduction; 4) new detection/surveillance methodology (onchocerciases urine test); microparticle controlled release of multivalent vaccines.
Discuss potential for a particular disease for widespread elimination or high levels of suppressive control – in a specific country of your choice
What are some of the challenges in the control and eradication of infectious diseases?
This paper should have the following sections:
- Burden of disease caused by the infectious disease – why is this a problem, including social, development and economic impact;
- Epidemiology of disease, including life cycle, mode of transmission, force of infection, R0 if known, any reservoirs (and specifically how these will be overcome), infectivity, virulence.
- SES, population and cultural factors (if appropriate) that may affect the implementation of your eradication/elimination plan in the chosen specific country.
- Control Tools: Known treatments, effective prophylaxis, tools for control, vector control capabilities, including a broad consideration of costs, if available/appropriate. You can include a description of plausible tools that are not yet developed, inclusive of mHealth, electronic surveillance or other digital or innovative technology.
- Propose an Elimination/Eradication Plan for a specific country/region.
- This should include a broad summary of the plan and its specific components (e.g. vector control, vaccination, mass treatment, environmental management).
- Describe how you would include high levels of stakeholder participation through communication strategies, incentive approaches. If appropriate, discuss the establishment of potential alliances such as public private partnerships (e.g. Rotary) that are possible/appropriate.
- Describe the frequency (i.e. how often for IRS, vaccination, mass treatment) and duration of anticipated program plan.
- Discuss potential anticipated barriers, problems, reasons for failure.
Potential Example Diseases (others acceptable but check with me):
- Hep A or Hep C
- Visceral leishmaniasis