Comparison of symptoms between Huntington’s and Parkinson’s diseases

Comparison of symptoms between Huntington’s and Parkinson’s diseases

Huntington’s disease

Parkinson’s disease

Personality changes, mood swings & depression
Forgetfulness & impaired judgment
Unsteady gait & involuntary movements (chorea)
Slurred speech, difficulty in swallowing & significant weight loss
Depression, irritability and anxiety
Stiffness of the limbs and trunk
Slowness of movement
Impaired balance and coordination, sometimes leading to falls
Resting tremor (trembling) in hands, arms, legs, jaw, or head

Answer the 3 questions below (400 words minimum),

1. Differentiate between chorea and resting tremor in their motor symptoms. Write down any similarities or differences below.
2. Based on the motor symptoms, can you come up with a hypothesis on which neurons are affected in Huntington’s disease ?

3. Can you explain the non-motor symptoms in these two diseases?